Title : Biomedical evaluation of antioxidant properties of iodine selenium and their combination in rat diets on the model of acute toxic hepatitis
Abstract:
The article presents a study of the antioxidant properties of lamb that was enriched with organic forms of iodine and selenium and used in the diets of laboratory animals on the model of acute toxic hepatitis. The experiments resulted in developing and testing a technique that was effective in enriching lamb with bioorganic elements of iodine and selenium and contributed to the activation metabolism in the bodies of animals consuming the meat. The purpose of the presented investigation was to compare roles of bioorganic iodine and selenium and their combination as antioxidants in rations for rats in a model of acute toxic hepatitis induced by carbon tetrachloride (CCl4). The experimental studies have established a hepatoprotective effect of lamb enriched with selenium and iodine, with xenobiotic toxically effecting the rat organism. This was confirmed by the normalized hematological and biochemical parameters of blood of the experimental rats.