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8th Edition of International Conference on

Nutrition and Food Sciences

March 26-28, 2026 | Singapore

Nutri 2026

Association between lipid accumulation product and stress urinary incontinence in US females: Mediation role of oxidative stress

Speaker at Nutrition and Food Sciences 2026 - Zhao Luo
Shenzhen Qianhai Taikang Hospital, China
Title : Association between lipid accumulation product and stress urinary incontinence in US females: Mediation role of oxidative stress

Abstract:

Purpose:
The relationship between lipid accumulation product (LAP) and stress urinary incontinence (SUI) in females remains unclear, and the potential mediating role of oxidative stress and inflammatory factors in this process has not been extensively studied. This analysis aims to explore the relationship between elevated LAP indices and SUI in women, with a particular focus on examining the mediating roles of oxidative stress and inflammatory factors in this association.

Methods:
Data from 4,292 participants across six consecutive cycles of the National Health and Nutrition Examination Survey (NHANES) were subjected to analysis. To investigate the association between LAP and the prevalence of SUI in adult women, various covariates were adjusted, logistic regression analysis and subgroup analysis were utilized. Additionally, mediation analysis was employed to evaluate the potential contributions of oxidative stress and inflammatory factors to this association.

Results:
The prevalence of SUI among US females was 46.02%. Following adjustment for confounding factors, the odds ratio (OR) for LAP and SUI was 1.003 (95% CI = 1.001-1.004, p = 0.002), indicating a positive correlation. Gamma-glutamyl transferase (GGT) mediated this relationship, explaining 40.0% of the effect (p = 0.036).

Conclusions:
The findings in this study indicate that LAP is positively associated with the prevalence of SUI in women, with oxidative stress potentially serving as a mediator in this relationship.

Keywords: Nutrition Surveys; lipid accumulation product; stress urinary incontinence; mediation analysis; oxidative stress.

Biography:

Dr. Luo Zhao, PhD (Jeonbuk National University). Key roles: Vice Chair of Shenzhen Urology Association Youth Committee, Standing Committee Member of Guangdong Male Health Association. International member: EAU, APSSM & ISSM. Holds positions in 5 Chinese medical associations. Awarded teaching honors at North Sichuan Medical College. Deputy Editor of Essential Diagnosis & Treatment of Urogenital Diseases. Led 2 municipal research projects. Received 2022 Andrology Innovation Award and 2023 National Urology Research Competition Award

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