Title : Nutrigenetics and precision nutrition as a tool for managing obesity and cardiovascular diseases
Abstract:
The estimated nutritional needs of individuals without a recognized ailment are reflected in public health nutrition guidelines that include reference intakes and recommended dietary allowances. In addition to preventing prevalent nutrition-related problems including obesity, diabetes, and cardiovascular diseases, these norms are meant to meet the dietary needs of the majority of a population. It is crucial to understand that reference intakes are not meant to treat patients with other illnesses or metabolic abnormalities. The recommendations are also not helpful to those with other common genetic variations because some of them are known to make people more susceptible to certain foods or nutrients, while others need higher intake to prevent disease as effectively as possible. For instance, two-thirds of the world's population cannot tolerate consuming large amounts of foods high in lactose, like milk. Another example is the fact that many women require significantly more folate than most others due to their genetic makeup in order to reduce their risk of producing children with birth abnormalities.
The capacity to combine various elements, including data from different "omics" data sources and the individual's genome, microbiome, and epigenome, is probably going to be essential to the success of precision nutrition.
Researchers can now screen thoroughly and evaluate the impact of genetic differences in complicated metabolic responses to particular meals, dietary recommendations, or individual nutrients thanks to new genetic techniques and nutritional scores. Therefore, by enabling the creation of tailored healthy lifestyle and nutrition guidance, nutrigenetics holds enormous promise as a tool for personalizing disease prevention, diagnosis and prognosis, and therapy in a wide range of nutrition, obesity, and other metabolic illnesses. Nutrigenetics is foreseen to be a potent instrument for complementing dietary advice in health care and prevention.